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    Thousands of accidents are witnessed everyday which range from minor to the major ones and cause death to many. All of the
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    se are a result of careless or aggressive driving. Below is a list of tips that should be kept in mind in order to play it
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    safe:

    Wear Your Seatbelt! -

    I cannot emphasize enough on the importance of wearing a seatbelt. You should always wear t
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    e seatbelt no matter how long or short your journey is.

    Obey the Law -

    The second most important thing is to know and ob
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ey the traffic rules. Red lights ask you to stop and not to speed up and run away.

    Look Around -

    As the traffic light tu
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    rns green you should look around. It might take few seconds but can avoid many life threatening collisions.

    Watch Your Sp
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ed -

    You should know the posted speed limits and keep your speed accordingly.

    Keep Distance -

    You should always maintai
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    n a distance of at least one car length especially near the congested areas in order to avoid rear-end accidents.

    Use Tur
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    n Signals -

    You should use turn signals and look before turning on to a major street from a residential neighborhood.

    Be
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    Calm -

    If someone else is breaking the rules don't do the same and don’t lose your control.

    Observe Warning Signs -

    You
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    should carefully observe the warning signs and drive accordingly.

    Observe Weather -

    You should drive according to the w
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    eather and the condition of the road.

    Avoid Cell Phones -

    You should avoid the use of cell phone while driving and even
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    f you’ve to use it try to make it minimum.

    Avoid Drink or Drugs -

    It is not recommended to drive after drinking or takin
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    g drugs. So you should avoid both of them while and before driving.

    Perform Regular Check Ups & Maintenance -

    You should
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    have a regular ‘check up’ of your vehicle by a professional mechanic. The below mentioned checks should be especially per
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    ormed on a regular basis:

    - Check Fluids: You should regularly check the battery and the radiator fluids especially in th
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    e extreme weather conditions.

    - Check Leakage: You should check that there is no leakage with a petroleum look or smell,
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    or green or pink colored water.

    - Check Tires: You should carefully check the tires and the spare, windshield wipers and
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    elts for abnormal wear.

    Thus, it is crystal clear we all can drive safely and avoid accidents by applying common sense pr
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    actices as well as following the traffic rules. I hope you’ll put these tips into action and will have a safe drive always


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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