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A lot of dogs and the Shih Tzu seen in vet offices are there for excessive scratching. What causes excessive scratching in the Shih Tzu and other canine breeds more than in cats, horses or a

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ny other animal species?

The three biggest reasons for excessive scratching include:

• Parasites
• Allergies
• Skin infections

There are many conditions, however, that causes dog

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

and the Shih Tzu to scratch. Some of these dogs and Shih Tzu have an itchy rash, they lose hair from the scratching, or their hair tangles into knots that has to be removed, or they may jus

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

scratch incessantly.

The flea is the most common parasite that will make a Shih Tzu scratch and itch incessantly. There are very effective flea treatments on the market today. If Shih Tzu

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

owners use these treatments as directed, they provide an effective way to protect the Shih Tzu from fleas and itching. Even Shih Tzu who stays indoors most of the time should receive regula

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

flea treatment to protect against fleas because fleas can be picked up in the backyard while going to potty or in the park while going for a walk.

Mites are another common parasite that can

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

cause the Shih Tzu to itch incessantly. Mites can also be effectively controlled with regular treatments.

Allergies are frequently the cause of intense scratching in the Shih Tzu and canine

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s in general. If your Shih Tzu is allergic to flea bites he can be miserable after only one flea bite.

Shih Tzu can also be allergic to environmental allergies such as seasonal pollens, mol

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s, and insects, and non-seasonal allergens such as house dust and house dust mites. These environmental allergies are similar to those people have. People usually sneeze or have congestion

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

n the nose. Shih Tzu usually itch from the same kind of allergens people will sneeze from.

Food allergies are another cause for a Shih Tzu to itch. The Shih Tzu may be allergic to one or m

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

re ingredients in the pet food you are feeding. Food allergies are usually less common, but can be quite severe.

Symptoms of environmental allergies can be treated with anti-inflammatory dr

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ugs, shampoos and other medications. Allergy testing and hypo sensitization will most likely be recommended to find the exact underlying cause or disease. Some allergens can just be simply

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

voided by you and your Shih Tzu.

The most accurate method used for identifying a dog or a Shih Tzu’s sensitivity to allergens is the intradermal skin testing. You must be certain your Shih

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

zu is off certain medications like steroids and anti-histamines to have accurate results from testing.

When you have identified the allergen that is troubling your Shih Tzu, you can avoid it

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

if possible. The Shih Tzu can also be hyposensitized to the offending allergen or allergens.

Another cause of scratching in the Shih Tzu and dogs in general is bacterial and yeast skin inf

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ctions. I have had personal experience with yeast ear and skin infections in some of my Shih Tzu. Usually a bath in Betodine Scrub every 7 days for 4 weeks takes care of this type of proble

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

. Pouring the Betodine Scrub directly into the ears provides wonders for these cases. I once had some kind of a little infection around one of my fingernails. It must have been due to yeas

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

t, because after I bathed one of my Shih Tzu who had the skin and ear yeast problem, the fingernail problem was cured within the next 24 hours.

Bacterial infections may look like small bumps

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

on the skin. Yeast skin infections are smelly and greasy as well as itchy. The infections are easily cured, but sometimes the underlying cause must be found if the infections are recurrent.

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

The causes to your Shih Tzu’s incessant itching can be found and remedied. Shih Tzu does not have to be tormented by constant itching.

This article is FREE to publish with the resource box

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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