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You can make your own supplement for general fish feeding that is high in DL-methionine (an import

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ant amino acid in fish nutrition); Start with whole salmon which is an excellent source of caroten

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e for color (frozen or even canned works), frozen peas, hard boiled egg, frozen or FD brine shrimp

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

, duck weed or spiulina powder, and fish oil (cod liver oil works fine). Blend this mixture then a

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

dd corn starch to the paste to dehydrate. Spread this paste on small strips of foil (or even wax p

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

aper if your dehydrator does not get to hot). Make sure you leave room for air circulation.

For a

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

frozen food, substitute the corn starch with unflavored gelatin powder.

For goldfish and koi, ad

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d wheat germ powder.

For more carnivorous fish increase the whole fish and decrease the spirulina

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

powder or duckweed. Calamari (squid) can be added too for carnivorous fish, but make sure that al

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

l the ink is removed from whole squid.

For spirulina powder, ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ucts.com/Spirulina20Food.html" target="_blank">Spirulina One Flake can be substituted, but sin

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ce this already a complete diet for many fish, I double the amount of this and decrease other ingr

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

edients by comparable amounts.

Here are basic percentages, please note that you can change these

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

percentages to suit your fish food requirements (for African cichlids use the goldfish formula exc

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ept delete the wheat germ):

BASIC/ GOLDFISH/ CARNIVOURE

Whole Salmon: 25% 20% 30%

Peas:

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

25% 25% 15%

Egg: 20% 15% 25%

Brine shrimp: 15% 15% 15%

Spirulina Powder: 10% 15%

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

5%

Wheat Germ: 0% 5% 0%

Squid: 0% 0% 5%

Fish Oil: 2% 2% 2%

Corn Starch or Gelatin

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

: 3% 3% 3%

For a complete article about what constitutes quality fish food ingredients, please

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

visit this article: elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

_blank">Quality Fish Food; What ingredients are needed for proper nutrition, growth and health

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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