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Dyeing wool seems like such a daunting task. It's really not as hard as you might think and it opens up an amaz

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ing new colorful world for your projects. These seven tips will get you started.

1. Relax. Deep breathe. Dyein

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

g wool is not really difficult. You will not ruin your wool. The first step is to stop being intimidated and ju

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

st take the plunge into coloring.

2. Don't try to achieve an exact color when you start dyeing wool. That way

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

you have no expectations and won't be disappointed with the final color.

3. Be sure and assemble ALL needed eq

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ipment and wool BEFORE you start dyeing wool. This will speed things along and be less frustrating for you.

4.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

Use the correct type of dye for wool. Acid dyes work best on protein (animal) fibers. Don't let the name scare

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

you. Acid dyes are not usually caustic. Food coloring is an acid dye. I like to use one shot dyes for coloring

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

wool. I don't have to mix anything. You just put it in boiling water and away you go. So far the dyes seem to

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

work great!

5. Dying wool takes a little time. I dedicate a whole day to the process so I only have to set-up

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nce. That way I can make lots of projects before I have to dye my fiber again. It's wonderful to have a lot of

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

colors on hand to grab when a project idea hits you.

6. Dye in smaller batches when you are first learning to

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

color fiber. After you get the hang of dyeing wool, you can dye larger amounts. Smaller amounts are much easier

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

to handle. If you don't like the color you make, then you are not stuck with a whole lot of a color that you j

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ust don't think you can use.

7. Start with just a few colors. Yellow, blue, red, and black are perfect. Using

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

our primary colors, you can mix up other colors without having to have a lot of dyes on hand. Black is just a g

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

reat color to have around This will be a little cheaper to begin dyeing. You can experiment making different co

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

lors, too, when you have to mix. Just write down the amount of dye used so you can reproduce it if you really l

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ike it.

These 7 tips should help you jump start your wool dyeing experience. You will be so excited to make ne

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

w projects with your hand dyed newly colored fiber. Dyeing wool is fun. Take a deep breath and color your world

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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