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  • Thesaurus - The Bugs At Bay

    (NC)-With approximately 42,000 mosquitoes for every person in Ontario, most of us s
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    pend a great deal of our summers swatting away these pesky insects. Protecting your
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    elf against mosquitoes will not only make your summer more enjoyable, it will help
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    revent you and your family from getting annoying and sometimes dangerous bug bites.
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

    As a family physician, I recommend the following tips for a bug free summer.

      d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

      Combination pro

    • Stay Scent-Free. Avoid using scented soaps, lotions and shampoos.

    • Gear Up
    • ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
      Cover your skin as completely as possible. This may be challenging by the beach, b
      easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
      ut when possible wear long sleeves, pants and socks.

    • Be Colour Conscious. Mosq
    • nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
      itoes are attracted to blue, so avoid this colour and stick to neutral colours.

      and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
      >Use Repellent. Repellents containing DEET are most effective for areas with heavy
      ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
      osquito or tick infestation.

    • Alternative Repellents. When applied frequently,
    • ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

      Following aspects would a
      itronella-based repellents can provide the same bug protection as products containi
      dd to the challenges in developing combination products:

      Which markets to tap where the combination products can do fairly well?
      Which combination prod
      g low concentrations of DEET. I recommend Natrapel®, which contains 10 percent citr
      cts are meaningful and rational?
      Which therapeutic categories to select?
      Which Combinations can address unmet needs of the patients?
      Do combin
      nella to ward off bugs for up to two hours.

    • Meal Time. Be alert to the time of
    • tions increase the patient compliance?
      What would be the developing cost?
      How to tackle the risks encountered during combination product developmen
      day when certain insects are most active such as dawn and twilight.

    • Check Poi
    • t?

      As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
      t. Upon returning indoors, check your children and yourself for bites.

    • Treatme
    • ping new procedures for reviewing their safety, efficacy and quality.

      Professional from academic institutions, pharmaceutical industries, health care indust
      t. Sunburn and bite treatment products should be included in every outdoor adventur
      y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
      r's travel kit.



      Dr. Brian Aw is a general practitioner specializing in trav
      .

      As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
      l medicine.

      For more tips on bug bite prevention and product information visit:
      elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

      Companies that provide selfless information through particip
      href="http://www.tendercorp.com/canada" target="_new">www.tendercorp.com/canada


      tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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