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There is a lot to know when you are a pool owner. Luckily there

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

are resources and articles such as this that can help reduce the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

complexity. Even if you are just keeping a contractor honest it

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s important to be a smart pool owner. This article helps simplif

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the selection of the right size filter for your swimming pool.

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

he correct filter size depends on the size of the pool. To maint

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ain a good water clarity you must run the pump each day so that

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ll the water in the pool is turned over once.

All filters have

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

allon per minute design rating and turnover rate. The minimum tu

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nover rate for your pool is one that turns over the entire pool

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nce in at least 10 hours. A turnover rate of 8 or 10 hours is th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e typical sizing rates for pools today.

The first thing that yo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

need to know is how many gallons of water are in your pool. A 4

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

deep 24' round pool has 13,500 gallons. Knowing this you can no

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

select a correctly rated filter.

Choose a filter that would at

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

a minimum turn your pool over i 10hrs. With filters it is OK to

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

go bigger. Larger filter areas will help maintain good water cla

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ity.

As an example: A 24 foot round above-ground pool has appro

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

imately 13,500 gallons. A Hayward S166T Sand Filter has a 10hr t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

rnover rate of 18,000 gallons and would work well with this pool

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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