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Many of us would love to build environmentally friendly additions or shop/storage/garage buildings. The trouble is that we d

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

on’t know where to start.

One simple way is to start with a kit for your building. Building kits reduce waste because compo

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nents are pre-cut and pre-measured. That way, there are no construction materials heading to the landfill.

“Reduce” is one

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

of the buzz-words for green construction. Reduce waste. Reduce water use. Reduce electrical use.

The next buzz-word is “R

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ecycle”. By using recycled building materials and components we are reducing materials heading to the landfill. By utilizin

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

metal building materials, you can ensure that at the end of the construction’s use, the materials are completely recyclable.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

We are all aware of the benefits of “Energy Efficient” components. High Efficiency heating units will save you operating c

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

osts for years to come. Even High Efficiency lights fixtures and light bulbs will save you money on an on-going basis. And

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

of course, purchase the most highly efficient appliances that your budget can afford. In this age of multiple appliances, th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ere can be huge saving in electricity which contributes to a greener environment.

“Re-use” wherever possible. By using recl

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

imed materials, you can save money. And creating a market for reclaimed materials again reduces landfill materials.

By simp

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ly installing water reducing shower faucets, you are adding “green” value to your construction or renovation project. Always

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

use low volume flush toilets to reduce the amount of wasted potable water.

Plan to build energy efficient walls, roof syste

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ms and floors. There are products and methods available to help achieve very energy efficient structures saving you heating

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

and cooling costs by reducing energy consumption.

Design your structures to take advantage of passive solar heating. Use ou

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

side landscaping to achieve passive air conditioning. For example, a south facing window will add sun-warmth in the winter.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

With a deciduous tree planted strategically, that same window will not super-heat your room in the summer.

You can even cle

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

an up the air in your home or office with the proper use of planting materials. Many “green” construction projects today are

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

including green walls or walls completely covered with plants and materials to increase the air and life-style quality.

Wit

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

h a little planning and effort, you too can boast that your construction project was built with a greener environment in mind

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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