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Water damage can come in many varieties, from a spilling a single bucket to

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

a complete basement flooding. How you approach your carpet clean up will a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

lso depend on the quality of the water if it is clean water, like rain wate

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

r, or is it from a sewer backup. Each situation should be evaluated on an i

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ndividual basis, but here are some general guidelines.

First the obvious t

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ry to stop the water at the source to eliminate further damage. Check behin

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

d the walls as water may be trapped in the insulation or behind the vapor b

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rrier. Next remove all furniture from the room, lift up the edges of the ca

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rpet and remove the uderpadding and discard. Extract as much of the water a

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

s possible, try to do this soon as you can, as bacteria and mold can set in

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

quickly.

Note – depending on the size and scope of damage it may be worth

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

calling in a professional. After you have extracted as much of the water a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

s possible treat the carpet with a disinfectant. Finally prop up the carpet

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

to let airflow get under the carpet and put fans throughout the room to sp

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ed up the drying process.

Unsanitary water has many more health issues and

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

concerns and you must take some precautions. Using rubber gloves and rubbe

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

r boots is a must. I would recommend calling in a professional technician t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

o handle this type of problem. The damage may not be isolated to just the c

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

arpeting it could extend to the drywall, insulation and wood studs. This ty

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

pe of water damage if not handled properly could pose a serious health risk

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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