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Egypt is one of Africa’s richest countries in terms of history. Egypt’s history goes back to the ancient times before the Bible. The biblical and cultural history of Egypt is as diverse and intriguing as the undiscovered tombs and cit

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ies lying underneath the desert sand in Upper and Lower Egypt.

Cairo is a city full of life. One aspect I quickly noticed when I set foot in Cairo is the traffic. Cairo is home to over 16 million inhabitants of which an additional 2

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

million people commute into the city in the morning and depart at sunset. In spite of the city having huge multiple-lane spaghetti highways, the traffic is extremely heavy. As you approach the city centre, a highway of 3 lanes is tune

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

into 5. The most notorious motorists are the taxis. As one drives in the city, one of your hands will permanently remain on the horn. I thought Nairobi had the worst traffic congestion in Africa, but Egypt for sure makes Nairobi’s tr

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

affic child-play.

The pyramids at Giza can be clearly seen from most parts of the city on a clear day. The Great Pyramids of Giza is such an imposing and monumental structure. It is absolutely mind-boggling to imagine that the ancien

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

man with limited technology and workmanship could put up such a huge structure. Of course, how the pyramids were built is a question of great global debate and may never be conclusively answered. Other theories even point to outer sp

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ace aliens as the sole builders of pyramids in Egypt.

The great pyramid of Cheops, which is the largest of the pyramids in Giza stands at height of 140 metres. It is a spectacular sight to arrive at the foot of the pyramid and just g

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ze at its sheer size. It is estimated that each block of stone weighs about 2.5 tons and over 2.3 million of these blocks were used to build this pyramid. It is estimated that the Great Pyramid of Cheops weight over 6 million tons. On

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e aspect that I noticed while viewing the pyramids from afar is the precise and exact structural design. Although most of the encasing marble was removed centuries ago and subsequently eroded by rain and sunshine, safe for the top mos

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

apexes, the triangular structural design is absolutely perfect.

The most intriguing aspect of the pyramid is the entry passage into its inner chambers. This is a task many people including myself found challenging. Anyone who is 6 f

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

eet tall like me will definitely run a sweat while trying to maneuver the way up the internal chambers of the pyramid. The entrance is about 1 meter square. This does not end there; I then realize that this is actually a stair case pa

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ssage rising at an angle. Have you ever tried climbing up a stair case in a crouch position? Imagine climbing stairs that the whole passage is 1 meter square. To make matters worse, it is summer time and the temperatures outside is ar

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

und 35 degrees Celsius. The stair case passage in the pyramid has no windows or air condition; so you can imagine how hot it is. Other passages descend as other go horizontal. Inside the pyramid are different burial chambers for the K

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ing and Queen. The tomb was of course robbed centuries ago and was found empty by archeologists. Any information about King Cheops was subsequently taken during the robberies and very little is known about him. He is thought to have b

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

en the ruler of a highly structured society and he must have been very wealthy. King Cheops was buried alone in this massive pyramid. It is estimated that his pyramid was built between 2589 - 2566 BC.

From the Pyramids, I visited the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Valley of Temple where dead kings were mummified. The mysterious Sphinx kept guard at the cemetery for over 5000 years.

Egypt will not be complete without a visit to the Egyptian Museum of Antiquities housing the largest collection

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

f Egyptian monuments in the world, 250,000 items. Here, you can also see the jewellery of the famous King Tut Ankh Amun, which dates back to 1352 B.C. A tour of the Citadel of Saladin is a must. This was built in 1176. The Alabaster

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

mosque of Mohamed Ali which was built on 1824 AD is also worth seeing.

In the evening I went for dinner in a floating restaurant while cruising down the River Nile. On board there was a beautiful belly dancer to entertain the diners

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nd a folkloric show. The cruise deck provides a beautiful night skyline of Cairo. The city is very well lit at night.

In the summer time, Cairo is mostly active during the night than during the day. This is due to the high temperatur

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

es experienced during the day. Stores, restaurants, malls etc remain open most of the night.

Other areas to visit in Egypt are Luxor, Alexandria and Sharm El Sheikh. A 4 day luxury cruise along the River Nile is an awesome experience

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Cheap Insurance is really right inside your own insurance policy. There are some myths worth discussing. One is, you don't have to wait for a policy renewal period to make changes with your carrier or a switch to a more competitive insurance company.

Anyone who has turned on the news, read a newspaper or visited a doctor's office in recent years likely knows that cholesterol can be a major problem for the body. It's all fine and well to tell people they need to lower cholesterol, but if they don't know what the buzz is all about, the words likely won't lead to action. So, lets take a good look at cholesterol, its dangers and how people can go about getting their cholesterol in check.

The pure passion of a La liga Football (Soccer) match in the Vicente Calderon stadium of Atletico Madrid. Feel that famous latin passion for the beautiful game as you experience the matchday atmosphere before, during and after the game itself. The smiles, cheers, tears an the rituals that go into the big game!

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